Regardless, you should experiment. If you wanted to harmonize the C phrygian scale, this is what you would get:
If you were to consider these chords as borrowed from phrygian and imported them to C major you would get this: i-bII-bIII-iv-Vo-bvi-bvii
You do sort of see this thing from time to time. You often get the bII and bIII in major keys and of course the minor iv chord (although the latter two usually considered borrowed from C minor).